Neuron-specific enolase concentrations in blood as a prognostic parameter in cerebrovascular diseases.

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Neuron-specific enolase concentrations in blood as a prognostic parameter in cerebrovascular diseases.

BACKGROUND AND PURPOSE To investigate the clinical relevance of plasma concentrations of neuron-specific enolase (NSE) in patients with severe cerebrovascular diseases, serial analyses were performed during the first 10 days after the acute event. METHODS Plasma samples taken from 61 patients (30 with brain infarction, 13 with intracerebral hemorrhage, 11 with cardiogenic hypoxia-ischemia, an...

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Neuron-specific enolase concentrations in serum in benign liver diseases.

Neuron-specific enolase (EC 4.2.1.11; NSE), a glycolytic enzyme produced by neuronal and neuroendocrine cells, is used as a tumor marker of neuroendocrine cancers, especially small-cell lung cancer. We have evaluated the behavior of NSE in nonmalignant liver diseases in 161 patients who underwent a thorough clinical and biochemical evaluation. Nine of the 161 patients (5.6%)--three of the 86 ci...

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Overexpression of Neuron-Specific Enolase as a Prognostic Factor in Patients with Gastric Cancer

PURPOSE Enolase is a cytoplasmic enzyme that catalyzes the conversion of 2-phosphoglycerate to phosphoenolpyruvate in the glycolytic pathway. The aim of this study was to investigate whether the overexpression of neuron-specific enolase (NSE) can serve as a prognostic factor in patients with gastric cancer (GC). MATERIALS AND METHODS To assess its prognostic value in GC, NSE expression was me...

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[Serum neuron-specific enolase as a prognostic marker after a cardiac arrest].

BACKGROUND AND OBJECTIVES Cardiac arrest is a state of severe cerebral perfusion deficit. Patients recovering from a cardiopulmonary resuscitation are at great risk of subsequent death or incapacitating neurologic injury, including persistent vegetative state. The early definition of prognosis for these patients has ethical and economic implications. The main purpose of this manuscript was to r...

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ژورنال

عنوان ژورنال: Stroke

سال: 1994

ISSN: 0039-2499,1524-4628

DOI: 10.1161/01.str.25.3.558